Aldosterone (Aldosterone, Serum)
The test determines the level of aldosterone — the adrenal cortex hormone participating in water-electrolyte balance and blood pressure regulation.
Aldosterone controls renal sodium reabsorption and potassium excretion, affecting circulating blood volume. Plays a key role in the renin-angiotensin-aldosterone system (RAAS). Applied to diagnose primary and secondary hyperaldosteronism (Conn's syndrome). Used when examining patients with resistant arterial hypertension.
What the test evaluates:
- Aldosterone concentration in blood serum
- RAAS activity
- Adrenal cortex hormonal function
Biomaterial: Venous blood
- Draw blood fasting
- Avoid physical and emotional stress 24 hours before
- Exclude blood pressure-affecting drugs 2 weeks before (by physician agreement)
- Maintain normal salt consumption before testing (unless physician prescribed otherwise)
Medications: Diuretics, ACE inhibitors, ARBs, beta-blockers may distort results
Medication discontinuation strictly by physician prescription
Recommended for:
- Suspected adrenal diseases and hormonal hypertension
- Resistant or early-onset arterial hypertension
- Electrolyte balance disorders and kidney diseases
- Persistent hypertension and hypokalemia
Elevated aldosterone: may indicate primary or secondary hyperaldosteronism
Reduced level: possible adrenal insufficiency or RAAS function disorder
Note: Assessment together with renin level and aldosterone-renin ratio calculation is recommended for accurate diagnosis.
