ANCA (antineutrophil cytoplasmic antibodies, IIFL, qualitative)
The test detects ANCA antibodies — autoantibodies directed against neutrophil cytoplasm. Used to diagnose systemic vasculitis (granulomatosis with polyangiitis, microscopic polyangiitis) and to monitor disease activity.
Biomaterial: Venous blood
- Draw blood fasting 8-12 hours;
- exclude alcohol 24 hours before;
- avoid stress and physical activity 30 minutes before.
- Inform physician of immunomodulator or anti-inflammatory drug intake.
- Recurrent or unusual vascular inflammatory processes;
- elevated ESR or CRP without cause;
- blood in urine or chronic kidney disorders;
- respiratory symptoms (cough, hemoptysis);
- suspected systemic vasculitis or autoimmune disease.
Negative — ANCA antibodies not detected.
Positive — ANCA antibodies detected; may indicate systemic vasculitis; further diagnostics required.
Note: Positive result is not a final diagnosis. Assessment by physician.
