Anti-dsDNA antibodies (anti-double-stranded DNA)
The test detects antibodies to double-stranded DNA — specific autoantibodies most often found in systemic lupus erythematosus (SLE). Used for diagnosis, disease activity assessment, and treatment monitoring.
Biomaterial: Venous blood
- Draw blood fasting 8-12 hours;
- exclude fatty food and alcohol 24 hours before;
- avoid stress and physical activity 30 minutes before.
- Inform physician of hormonal, immune, or anti-inflammatory drug intake.
- Suspected systemic lupus erythematosus;
- joint and muscle pain;
- skin rashes, especially on face;
- elevated temperature without cause;
- edema, urine changes;
- elevated ESR and inflammation signs;
- positive ANA result.
Negative — antibodies not detected.
Positive — anti-dsDNA antibodies detected; may indicate systemic lupus erythematosus.
Note: Antibody level may increase with disease activity. Final diagnosis made by physician.
