Anti-MPO (MPO-ANCA) antibodies, quantitative (ICL)
The test quantitatively determines antibodies to myeloperoxidase (MPO-ANCA) — autoantibodies associated with ANCA-associated vasculitis. Used for diagnosis, disease form clarification, vasculitis activity assessment, and therapy monitoring. Elevated MPO-ANCA characteristic of microscopic polyangiitis, eosinophilic granulomatosis, and other ANCA-associated vasculitis.
Biomaterial: Venous blood
- Draw blood fasting 8-12 hours (no water);
- exclude alcohol 24 hours before;
- avoid stress and physical activity 30 minutes before.
- Inform physician of immunomodulator, hormonal, or anti-inflammatory drug intake.
- Suspected systemic vasculitis;
- kidney involvement (proteinuria, hematuria, reduced function);
- prolonged fever of unclear origin;
- joint and muscle pain;
- skin rashes, hemorrhages;
- lung or ENT organ involvement;
- previously diagnosed vasculitis activity monitoring.
Negative — anti-MPO antibodies not detected.
Positive — anti-MPO antibodies detected; indicates ANCA-associated vasculitis.
Note: Assessment conducted only together with clinical symptoms and other studies.
