Anti-Scl-70 IgG antibodies, quantitative (ICL)
Detects antibodies to Scl-70 protein (topoisomerase I) for systemic scleroderma (SSc) diagnosis.
Biomaterial: Venous blood
- Draw blood fasting
- Water is permitted
- Exclude alcohol 24 hours before
- Avoid stress 30 minutes before
- Suspected systemic scleroderma;
- skin changes, Raynaud's phenomenon;
- joint pain, fatigue;
- internal organ involvement;
- autoimmune disease monitoring.
Negative — anti-Scl-70 not detected.
Positive — characteristic of SSc.
Rheumatologist consultation recommended.
