Anti-ssDNA antibodies (anti-single-stranded DNA)
The test detects antibodies to single-stranded DNA — autoantibodies that may appear with various autoimmune diseases. Used as an additional marker in systemic connective tissue disease diagnosis.
Biomaterial: Venous blood
Draw blood fasting 8-12 hours; exclude fatty food and alcohol 24 hours before; avoid stress and physical activity 30 minutes before. Inform physician of hormonal, immune, or anti-inflammatory drug intake.
- Suspected autoimmune diseases;
- joint and muscle pain;
- chronic weakness and fatigue;
- skin rashes;
- elevated temperature without cause;
- positive ANA result;
- autoimmune process activity monitoring.
Negative — antibodies not detected.
Positive — anti-ssDNA antibodies detected; may indicate autoimmune process.
Note: Test is not used as sole diagnostic criterion. Physician assessment considering other studies.
