Antibodies to denatured DNA (single-stranded, quantitative)
Detects antibodies to single-stranded (denatured) DNA for SLE diagnosis and activity monitoring.
Biomaterial: Venous blood
- Draw blood fasting (8-12 hours without food)
- Exclude alcohol 24 hours before
- Avoid stress and physical activity 30 minutes before
- Suspected SLE;
- joint/muscle pain, skin rashes;
- elevated temperature; kidney involvement;
- autoimmune disease activity monitoring.
Negative — anti-ssDNA not detected.
Positive — characteristic of SLE.
Rheumatologist consultation recommended.
