APTT (Activated Partial Thromboplastin Time)
APTT is used to assess intrinsic and common blood coagulation pathways. Allows detection of hemostasis system disorders, assessment of bleeding or thrombosis risk, and monitoring of anticoagulant therapy efficacy.
Test composition:
- Material: venous blood
- Method: coagulometric method
- Measured indicator: blood clot formation time upon intrinsic coagulation pathway activation
- Units: seconds
- Deviation causes: prolonged APTT — coagulation factor deficiency, coagulation inhibitor presence, anticoagulant therapy, or liver diseases. Shortened — elevated blood clotting and thrombosis risk.
Biomaterial: Venous blood
- Draw blood fasting
- Exclude alcohol 24 hours before
- Avoid physical activity and stress before testing
Medications:
Inform physician of anticoagulant, antiplatelet, or hormonal drug intake before testing
Prescribed for:
- Suspected blood clotting disorders
- Unexplained bleeding or thrombosis tendency
- Liver diseases
- Autoimmune diseases and antiphospholipid syndrome
- Heparin therapy monitoring
- Preoperative preparation
Recommended for:
- Patients with suspected hemostasis disorders
- People with cardiovascular diseases
- Pregnant women
- Pre-surgery patients
Reference values depend on methodology used and are indicated on result form.
Deviations require physician consultation and comprehensive assessment.
Note: APTT is not used as standalone diagnostic criterion and evaluated together with other coagulation indicators.
With deviations, consultation with general practitioner, hematologist, or cardiologist is recommended.
