Blood Microreaction (RPR Screening)
Purpose of the test:
- Blood microreaction is a laboratory test for detecting inflammatory and pathological processes in the body at early stages.
- Used to assess immune system status, detect hidden infections and inflammation, and monitor syphilis treatment efficacy and other infectious processes.
- The test is particularly informative for prolonged or unclear inflammatory processes, elevated ESR and leukocyte counts, fevers, and general intoxication.
What the test assesses:
- Leukocytes — detecting inflammatory process.
- Erythrocytes — tissue damage or hidden bleeding.
- Blood color and clarity — indirect indicators of blood composition changes.
- Plasma protein — possible inflammatory reactions.
- Erythrocyte aggregates — signs of inflammation activation.
- Plasma status — presence of pathological changes affecting clotting and cellular composition.
Biomaterial: Venous blood
- Submit fasting.
- Avoid physical and emotional exertion before the test.
Medications: if possible, avoid taking drugs affecting blood composition (anticoagulants, anti-inflammatory drugs, corticosteroids, antibiotics) 24-48 hours before the test.
Recommended for testing:
- when syphilis is suspected
- with unexplained ulcers or rashes on skin or mucous membranes
- with lymph node enlargement without obvious cause
- before hospitalization or surgical procedures
- for pregnant women (as part of mandatory screening)
- as part of preventive medical examinations
- for people who have had unprotected sexual contact
- for contact with a person diagnosed with syphilis
- Negative result: no signs of inflammation or infection, microreaction shows no pathological changes.
- Positive result: possible inflammatory processes, hidden infections, active syphilitic process; requires additional confirmatory test (treponemal test).
- Questionable result: requires repeat testing and/or additional diagnostics to clarify the cause of changes.
