Cytomegalovirus DNA, Oropharyngeal Epithelial Cell Scraping (PCR)
The study is conducted to detect cytomegalovirus (CMV) DNA by PCR in oropharyngeal epithelial cells.
Used for diagnosing local cytomegalovirus infection of the oropharynx.
Applied for prolonged sore throat, inflammatory mucosal lesions of unclear origin, and tonsillitis of atypical course.
Prescribed for patients with immunodeficiency and weakened immunity, including HIV-infected, oncological, and transplant patients.
Allows determination of CMV's involvement in the oropharyngeal inflammatory process and assessment of the need for antiviral treatment.
What the test assesses:
– Presence of CMV DNA in oropharyngeal epithelial cells.
– Local viral infection activity.
– Possible viral involvement in the development of oropharyngeal inflammation and lesions.
Biomaterial: Oropharyngeal epithelial cell scraping
– Do not treat the oral cavity with antiseptics for 24-48 hours.
– Do not eat, drink, or brush teeth immediately before collection.
– Avoid mechanical irritation of the throat area on the day of the test.
Medications:
– If possible, discontinue antiviral medications 48-72 hours before.
– Do not use local antibacterial and antiseptic agents for 5-7 days.
– If discontinuation is not possible, be sure to inform the doctor of all medications taken.
Recommended for testing:
– With oropharyngeal lesions of unclear etiology, prolonged sore throat, and atypical tonsillitis.
– When CMV infection is suspected in patients with oropharyngeal manifestations.
– With decreased immunity and viral activity monitoring.
– With immunosuppressive therapy and CMV reactivation risk.
– Positive result: CMV DNA detected in oropharyngeal cells, indicating active viral involvement in the inflammatory process. Clinical significance assessment is required, and if necessary, antiviral treatment.
– Negative result: CMV DNA not detected; active infection is unlikely.
Important — results are interpreted together with the clinical picture, serological tests (IgG/IgM), and concomitant tests.
