D-Dimer
D-dimer is a fibrin breakdown product formed during active thrombus formation and subsequent fibrinolysis.
The test allows detection of thrombi, assessment of thromboembolic complication risk, and monitoring of anticoagulant therapy efficacy.
D-dimer is widely used in diagnosing deep vein thrombosis, pulmonary embolism, and coagulopathies.
Test composition:
• Material: venous blood (plasma)
• Method: immunoturbidimetry or enzyme immunoassay (ELISA)
• Determined indicator: D-dimer concentration in plasma (ng/mL or µg/L)
Causes of abnormalities: elevation — thrombosis, thromboembolism, inflammatory processes, liver diseases, pregnancy, and after surgical procedures. Low level — low thrombosis and fibrinolysis activity.
Biomaterial: Venous blood (plasma)
• Submit blood fasting
• Avoid alcohol for 24 hours.
• Avoid physical exertion and stress before the test.
Medications:
• If taking anticoagulants, antiplatelet agents, or hormonal medications, inform the doctor before the test.
Prescribed for:
• Suspected deep vein thrombosis and pulmonary embolism.
• Tendency to thrombosis.
• Monitoring anticoagulant therapy.
• During pregnancy with thrombophilia risk.
• After surgical procedures and injuries.
Recommended for:
• Patients with suspected thrombosis, thromboembolism
• Patients with cardiovascular diseases
• Pregnant women with high thrombophilia risk
Reference values depend on the laboratory method and are indicated on the result form.
Abnormalities require physician consultation and comprehensive assessment.
Important — D-dimer is assessed together with other coagulogram indicators and is not a standalone diagnostic criterion for thrombosis.
If abnormalities are detected, consultation with a general practitioner, hematologist, or cardiologist is recommended.
