Epstein-Barr Virus, Early Antigen IgG (EBV EA IgG, Serum)
The study is aimed at detecting IgG class antibodies to the early antigen (EA) of the Epstein-Barr virus.
Used for assessing EBV infection activity and detecting virus reactivation in chronic course.
Prescribed for symptoms characteristic of prolonged or reactivated EBV infection: chronic fatigue, low-grade fever, enlarged lymph nodes, night sweats.
Applied for monitoring chronic EBV infection and assessing viral activity against the background of immune disorders.
Used in comprehensive diagnosis of EBV-associated diseases.
What the test assesses:
– Presence or absence of IgG antibodies to the EBV early antigen.
– Activity of the viral process or its reactivation.
– Indirect signs of ongoing virus replication.
Biomaterial: Venous blood (serum)
– Submit fasting (8-12 hours after the last meal).
– Drinking still water is allowed.
– It is advisable to exclude intense physical exertion and stress within 24 hours.
Medications:
– Antiviral therapy may decrease antibody levels and affect result interpretation.
– Immunomodulators and immunoglobulins can distort serological indicators.
– Medication intake should be coordinated with the doctor and be sure to be indicated when submitting the test.
Recommended for testing:
– When active or reactivated EBV infection is suspected.
– With prolonged asthenia, chronic fatigue, low-grade fever of unclear origin.
– With immunodeficiency conditions and immune response disorders.
– With lymphoproliferative conditions, persistent lymphocytosis, changes in complete blood count.
– Positive result (EA IgG detected): possible active infection phase or EBV reactivation; characteristic of chronic active EBV infection; may be detected in EBV-associated diseases.
– Negative result (EA IgG not detected): no signs of active virus replication; latent (inactive) form of EBV infection.
Important — for correct interpretation, it is recommended to assess the result together with VCA IgM, VCA IgG, and EBNA IgG, and if necessary, with PCR diagnostics.
