Estradiol (E2) — primary female sex hormone blood test
The test determines the level of estradiol (E2) — the primary and most biologically active estrogen in women. Estradiol is synthesized predominantly by the ovaries, to a lesser extent by the adrenal glands and adipose tissue. The hormone plays a key role in menstrual cycle formation, follicle maturation, ovulation, and reproductive function maintenance. Affects endometrial growth, breast condition, bone density, vascular elasticity, and emotional state.
What the test evaluates:
- Estradiol concentration in blood serum
- Ovarian functional activity
- Hormonal level correspondence to menstrual cycle phase
Biomaterial: Venous blood
- Draw blood fasting
- Menstrual cycle day — by physician prescription (usually day 3-5)
- Exclude physical activity and stress 24 hours before
Medications:
- Hormonal drugs and oral contraceptives may affect results
- Medication discontinuation only by physician agreement
Recommended for:
- Cycle disorders, infertility
- IVF and other ART program preparation
- Hormonal imbalance
- Hormone-dependent neoplasms
Elevated level: possible with follicular cysts, estrogen-producing tumors, obesity
Reduced level: characteristic of anovulation, ovarian depletion, menopause, hypopituitarism.
