Extended serological diagnostics of bullous dermatoses — epidermis, pemphigoid antigens, BP180-NC16A-4X, BP230-CF, desmoglein 1, desmoglein 3 — titer
Detects autoantibodies to specific skin antigens for bullous dermatosis diagnosis (pemphigus, pemphigoid).
Profile: Desmoglein 1 (pemphigus — intracutaneous epidermal connections); Desmoglein 3 (pemphigus — mucous membranes/skin); BP180-NC16A-4X (pemphigoid — epidermal basement membrane); BP230-CF (pemphigoid — basement membrane/keratinocyte cytoplasm); Epidermis antigens; Pemphigoid antigens
Biomaterial: Venous blood
- Draw blood fasting (8-12 hours without food)
- Exclude alcohol 24 hours before
- Avoid stress and physical activity 30 minutes before
- Vesicular or bullous skin and mucosal rashes;
- itching and pain from rashes;
- suspected autoimmune skin damage;
- disease activity and treatment monitoring.
Negative — antibodies not detected.
Positive — autoantibodies to specific skin antigens detected; confirms bullous dermatosis.
Results evaluated with clinical picture and other methods.
Recommended physicians: Dermatologist or rheumatologist experienced in autoimmune skin diseases.
