Fecal calprotectin
The test determines the level of fecal calprotectin — the protein released by neutrophils during intestinal mucosal inflammation. A sensitive and non-invasive inflammatory bowel disease (IBD) marker. Used to differentiate organic inflammatory diseases (Crohn's disease, ulcerative colitis) from functional disorders (irritable bowel syndrome). Applied to assess inflammatory process activity and treatment efficacy monitoring.
What the test evaluates:
- Calprotectin concentration in stool
- Presence and severity of intestinal inflammation
- GI mucosal inflammatory process activity
Biomaterial: Stool
- No special diet required
- Exclude NSAIDs (ibuprofen, diclofenac, etc.) 3-5 days before if possible
- Do not perform during acute intestinal infection without physician prescription
- Collect stool in sterile container
Medications:
- NSAIDs may elevate calprotectin level
- Antibiotics and laxatives may affect results
- Medication discontinuation by physician agreement
Recommended for:
- Suspected IBD and therapy monitoring
- Prolonged intestinal complaints
- Chronic diarrhea and abdominal pain in children
- Inflammatory bowel diseases
Normal/low level: intestinal inflammation unlikely; more often corresponds to functional disorders (IBS)
Elevated level: indicates inflammation (IBD, intestinal infections, diverticulitis, tumor processes)
High values: characteristic of active Crohn's disease and ulcerative colitis phase
Note: Result always evaluated together with clinical data and other studies.
Result on the day of the request
