Fibrinogen, Clauss Method
The Clauss fibrinogen test is used for precise quantitative determination of fibrinogen level in blood plasma.
This method allows assessment of blood clotting ability, detection of coagulation disorders, and monitoring of anticoagulant therapy efficacy.
Test composition:
• Material: venous blood
• Method: Clauss method — coagulometric method with calcium chloride and thromboplastin
• Determined indicator: fibrinogen concentration in blood plasma (g/L)
Causes of abnormalities: elevation — inflammation, stress, infections, cardiovascular diseases, or pregnancy. Decrease — acute bleeding, hereditary fibrinogen synthesis disorders, liver diseases, or anticoagulant use.
Biomaterial: Venous blood
• Submit blood fasting
• Avoid alcohol for 24 hours.
• Avoid physical exertion and stress before the test.
Medications:
• If taking anticoagulants, antiplatelet agents, or hormonal medications, inform the doctor before the test.
Prescribed for:
• Suspected blood clotting disorders.
• Bleeding tendency or thrombosis tendency.
• Liver diseases.
• Inflammatory processes.
• Monitoring anticoagulant therapy.
• Before surgical procedures.
Recommended for:
• Patients with hemostasis disorders
• People with cardiovascular diseases
• Patients before surgery
Reference values depend on the laboratory method and are indicated on the result form. Abnormalities require physician consultation and comprehensive assessment.
Important — Clauss fibrinogen level is assessed together with other clotting indicators and is not a standalone diagnostic criterion.
If abnormalities are detected, consultation with a general practitioner, hematologist, or cardiologist is recommended.
