Free PSA (Prostate-Specific Antigen, Free)
Used together with total PSA to clarify probability of malignant process in the prostate gland. Allows differentiation of benign and malignant prostate diseases. Applied with borderline total PSA values to improve diagnostic accuracy. Used to calculate free-to-total PSA ratio, which has diagnostic value.
What the test evaluates:
- Free fraction PSA level in blood serum
- Free-to-total PSA ratio reflecting the nature of pathological process in the prostate gland
Biomaterial: Venous blood
- Draw blood fasting
- Abstain from ejaculation 48 hours before
- No prostate massage or instrumental prostate studies 5-7 days before
Medications:
- Prostate treatment drugs may affect PSA level
- Inform physician of all medications taken
Recommended for:
- Urologist — for diagnosis clarification with suspected prostate diseases
- Oncologist — with elevated total PSA and suspected prostate cancer
- General practitioner — with borderline total PSA values in primary examination
Important: Results evaluated only together with total PSA level and clinical data.
Normal: high free PSA proportion relative to total; benign changes (adenoma, prostatitis) more probable
Deviations: low free-to-total PSA ratio — elevated malignant process risk; urologist consultation required and, if necessary, additional examination (PHI index, MRI, biopsy).
CITO-analyses
Result on the day of the request
Result on the day of the request
