Gastropanel + Gastrin-17 stimulated
Comprehensive diagnostics of gastric diseases. Assessment of gastric acid production (hypo- or hypersecretion). Detection of atrophic gastritis and precancerous mucosal changes. Diagnosis of Helicobacter pylori infection.
Used for early detection of gastropathies associated with elevated peptic ulcer and gastric cancer risk. Allows determination of gastric functional condition without invasive endoscopy, and monitoring of chronic gastritis and H. pylori patients.
What the test evaluates:
- Pepsinogen I and II levels and PG I/PG II ratio — mucosal atrophy indicator
- Gastrin-17 level (stimulated) — reflects acid production and functional status of gastric antrum
- Presence of H. pylori antibodies — infection and mucosal inflammation risk marker
- Complex indicator allows differentiation of atrophic gastritis from functional disorders
Biomaterial: Venous blood
- Draw blood strictly fasting, per laboratory instructions
- Exclude food, beverages, and smoking 8-12 hours before
- Exclude intense physical activity and stress 24 hours before
Medications:
- Proton pump inhibitors, antacids, and gastroprotectors significantly affect results
- Medication discontinuation only by physician prescription
- Inform physician of all medications taken
Recommended for:
- Dyspepsia, chronic gastritis, suspected atrophic gastritis
- Patients with family predisposition to gastric cancer
- Patients after H. pylori treatment — for mucosa recovery monitoring
- With heartburn, epigastric pain, nausea, dyspepsia symptoms
Results interpreted together with clinical data and endoscopic study if performed.
Normal: pepsinogens and PG I/PG II ratio within normal range; gastrin-17 stimulated corresponds to reference values; negative H. pylori marker; gastric mucosa without atrophy signs
Deviations:
- reduced PG I/PG II ratio — atrophic gastritis, precancerous change risk;
- elevated gastrin-17 — reduced acid production, possible antral atrophic process;
- positive H. pylori — active or past infection;
- further diagnostics and gastroenterologist consultation required.
