Giardiasis (Giardia lamblia) IgA antibodies
Detects IgA antibodies to Giardia lamblia — parasites affecting the small intestine causing digestive disorders, intoxication, and allergy-like reactions. IgA are mucosal immunoglobulins, making this test often viewed as a marker of active intestinal process.
Used for:
- detecting immune response to giardia with GI symptoms;
- clarifying cause of chronic abdominal discomfort, bloating, diarrhea;
- children with frequent intestinal disorders;
- complex diagnostics together with IgG/IgM and stool tests.
Note: serology (antibodies) does not always confirm current parasite presence. For active infection confirmation, physician often orders stool antigen/PCR since giardia lives in the intestine.
Infection routes:
- dirty hands;
- water (including unboiled);
- unwashed/poorly washed vegetables/fruits;
- contact-household (especially in children's groups).
Recommended for:
- children (kindergarten, school);
- prolonged GI symptoms;
- frequent unexplained allergies;
- weight loss, poor appetite;
- elevated eosinophils.
Biomaterial: Venous blood
Draw blood fasting (8-12 hours without food)
Water is permitted
Exclude fatty food and alcohol 24 hours before
No smoking 30 minutes before
Medications: If taking antiparasitic drugs, hormonal drugs, or immunosuppressants — inform physician; dose adjustment is usually not required unless directed by physician
- Prolonged bloating, rumbling, abdominal pain;
- unstable stool (diarrhea/constipation alternation);
- nausea, reduced appetite;
- bad breath, coated tongue;
- weakness, fatigue, 'intoxication';
- unexplained allergic manifestations (rash, itching, urticaria);
- elevated eosinophils;
- frequent intestinal complaints in children.
Note: IgA is more associated with process activity, but diagnosis confirmation usually requires additional stool tests.
Negative IgA — antibodies not detected (active process unlikely or early infection stage).
Positive IgA — organism reacting to giardia; may be: active infection, chronic process exacerbation.
At positive result: gastroenterologist or infectious disease specialist/parasitologist consultation for confirmation and treatment.