Myasthenia Diagnostics: Muscle-Specific Tyrosine Kinase (MUSK) Antibodies — Acetylcholine Receptor Antibodies, IIF, Titer
The test detects antibodies to acetylcholine receptors (AChR) and muscle-specific tyrosine kinase (MUSK). Used for diagnosing myasthenia gravis — an autoimmune disease in which nerve impulse transmission to muscles is impaired.
Profile composition:
Muscle-specific tyrosine kinase (MUSK) antibodies, IIF, titer
Acetylcholine receptor (AChR) antibodies, IIF, titer
Biomaterial: Venous blood
- Submit fasting (8-12 hours without food)
- Avoid alcohol for 24 hours
- Avoid stress and physical exertion 30 minutes before
- If taking immunomodulators, hormonal, or anti-inflammatory medications — inform the doctor.
- muscle weakness worsening toward evening
- drooping eyelids (ptosis)
- double vision
- difficulty chewing, swallowing, speaking
- rapid muscle fatigue
- suspected myasthenia gravis
Negative result — antibodies not detected.
Positive result:
AChR antibodies — characteristic of the classic form of myasthenia gravis
MUSK antibodies — characteristic of MUSK-associated myasthenia gravis
Important: the result is assessed only in combination with clinical symptoms and other tests.
