Phagocytosis (NBT test) (Nitroblue Tetrazolium Test, Blood)
The test is aimed at assessment of phagocyte (neutrophil) functional activity.
Used for diagnosis of cellular immunity disorders. Prescribed for frequent and severe infections.
What the test evaluates:
- Neutrophil capacity for intracellular destruction of microorganisms
- Functional state of the phagocytic immunity link
Biomaterial: Venous blood
- Draw blood fasting
- Exclude physical activity 24 hours before
Medications:
Glucocorticosteroids, immunomodulators, and cytostatics may affect results
Recommended for:
- Suspected phagocytosis defects
- Frequent bacterial infections
- Recurrent infections in children
Important: Results evaluated in combination with clinical data and other immunity markers.
Normal: neutrophil phagocytic activity within normal range; body's ability to effectively destroy microorganisms preserved
Reduced activity: reduced phagocytic function; may indicate immunodeficiency or increased infection susceptibility
Increased activity: enhanced phagocytic function; may occur with acute infections or inflammatory processes
Physician consultation required for deviations.
