Quantitative Determination of Antimitochondrial Antibodies (AMA-M2), ICL
The test detects antimitochondrial antibodies class M2 (AMA-M2), which are a specific marker of primary biliary cholangitis (PBC). Used for disease diagnosis, activity assessment, and therapy monitoring.
Composition (antibodies):
AMA-M2 (antimitochondrial antibodies M2) — specific marker of primary biliary cholangitis
Biomaterial: Venous blood
- Submit fasting (8-12 hours without food)
- Avoid alcohol for 24 hours
- Avoid stress and physical exertion 30 minutes before
- elevated liver enzymes (alkaline phosphatase, AST, ALT, GGT) without obvious cause
- symptoms of chronic liver damage: fatigue, skin itching, jaundice
- suspected primary biliary cholangitis
- monitoring activity of already diagnosed PBC
Negative result — mitochondrial antibodies not detected.
Positive result — AMA-M2 antibodies detected, characteristic of primary biliary cholangitis.
Important: the result is assessed together with clinical data and other laboratory tests.
