Rehberg Test (Creatinine Clearance)
The test assesses kidney function through determining creatinine clearance — the kidneys' ability to filter blood and excrete metabolic products. Used for diagnosing chronic kidney disease and monitoring its course.
Mechanism of abnormalities: decreased creatinine clearance indicates worsening kidney filtration function. Elevated values are rare and require physician assessment.
Recommended for:
- people with chronic kidney diseases
- with swelling or elevated blood pressure
- for monitoring kidney disease treatment
- with suspected decreased kidney function
Biomaterial: Venous blood, 24-hour urine
- Submit fasting (8-12 hours without food)
- Do not drink water
- Collect urine over 24 hours according to laboratory instructions
- Avoid alcohol and excessive physical exertion for 24 hours
- Avoid stress
Medications: if taking diuretics, heart, or kidney medications — inform the doctor
- Suspected renal failure
- Chronic kidney diseases
- Swelling, elevated blood pressure
- Decreased urine volume
- Monitoring therapy efficacy in kidney diseases
Normal — creatinine clearance within reference values considering age and sex
Decreased clearance — signals decreased kidney function
Which doctor to consult:
If kidney function disorder is suspected or test abnormalities are detected, consultation with a nephrologist is recommended. The doctor evaluates laboratory results, clarifies clinical symptoms, and if needed prescribes treatment or additional tests.
Self-treatment is not recommended!
