Thrombin time
Thrombin time assesses the final stage of blood coagulation — fibrinogen-to-fibrin conversion. Allows detection of clotting disorders related to fibrinogen deficiency or dysfunction, coagulation inhibitor presence, and monitoring of anticoagulant therapy efficacy.
Test composition:
- Material: venous blood
- Method: coagulometric method
- Measured indicator: fibrin clot formation time after thrombin addition to patient plasma
- Deviation causes: prolonged — reduced fibrinogen level, its structural disorder, coagulation inhibitor presence, or anticoagulant intake. Shortened — observed less often, may indicate elevated clotting.
Biomaterial: Venous blood
- Draw blood fasting
- Exclude alcohol 24 hours before
- Avoid physical activity and stress before testing
Medications:
Inform physician of anticoagulant, antiplatelet, or hormonal drug intake before testing
Prescribed for:
- Suspected blood clotting disorders
- Bleeding or thrombosis tendency
- Liver diseases
- Anticoagulant therapy monitoring
- Preoperative preparation
Recommended for:
- Patients with hemostasis disorders
- People with cardiovascular diseases
- Pre-surgery patients
Reference values depend on laboratory methodology and are indicated on result form.
Deviations require physician consultation and comprehensive assessment.
Note: Thrombin time evaluated together with other coagulation indicators and not used as standalone diagnostic criterion.
With deviations, consultation with general practitioner, hematologist, or cardiologist is recommended.
