Toxoplasmosis (Toxoplasma gondii) IgG antibodies
Detects IgG antibodies to Toxoplasma gondii — an intracellular parasite causing toxoplasmosis. Infection most commonly occurs through consuming insufficiently cooked meat, unwashed vegetables/fruits, and contact with soil or cat litter. Used to determine past infection and immunity presence — especially important during pregnancy and pregnancy planning.
Infection routes:
- poorly cooked/raw meat;
- unwashed vegetables/fruits/berries;
- contact with cat litter, soil, sand contaminated with oocysts.
Recommended for:
- pregnant women and those planning pregnancy;
- cat owners;
- immunocompromised patients.
Biomaterial: Venous blood
- Draw blood fasting (8-12 hours without food)
- Water is permitted
- Exclude fatty food and alcohol 24 hours before
- No smoking 30 minutes before
Medications: If taking antiparasitic drugs, hormonal drugs, or immunosuppressants — inform physician; dose adjustment is usually not required unless directed by physician
- Pregnancy planning;
- pregnancy (TORCH screening);
- enlarged lymph nodes, weakness;
- reduced immunity; s
- uspected intrauterine infection.
Note: IgG more often shows past toxoplasmosis. To assess infection recency, physician considers IgM and avidity.
Negative IgG — antibodies not detected; organism was not previously infected and has no immunity.
Positive IgG — contact with toxoplasma (usually past infection).
At positive result: infectious disease specialist/parasitologist consultation. At pregnancy: infectious disease specialist and gynecologist consultation recommended.