Toxoplasmosis (Toxoplasma gondii) IgM antibodies
Detects IgM antibodies to Toxoplasma gondii — early immune response antibodies appearing in the first weeks after infection. Used to detect recent or current infection — especially important during pregnancy and suspected primary infection.
Special considerations:
- IgM may appear before IgG but can sometimes persist long after acute infection subsides;
- a single IgM(+) does not always indicate acute infection;
- to clarify infection timing, physician usually orders avidity, IgG, and/or repeat testing.
Infection routes:
- poorly cooked meat;
- unwashed vegetables/berries;
- contact with cats/soil.
Recommended for:
- pregnant women/those planning pregnancy;
- immunocompromised patients.
Biomaterial: Venous blood
- Draw blood fasting (8-12 hours without food)
- Water is permitted
- Exclude fatty food and alcohol 24 hours before
- No smoking 30 minutes before
Medications: If taking antiparasitic drugs, hormonal drugs, or immunosuppressants — inform physician; dose adjustment is usually not required unless directed by physician
- Pregnancy/pregnancy planning;
- suspected acute infection;
- stage clarification when IgG(+/-).
Negative IgM — acute infection unlikely.
Positive IgM — possible recent infection (avidity check and consultation needed).
At positive result: infectious disease specialist/parasitologist consultation. At pregnancy: infectious disease specialist and gynecologist consultation recommended.
